Date of this Version
Lesion analysis in brain-injured populations complements what can be learned from functional neuroimaging. Voxelbased approaches to mapping lesion–behavior correlations in brain-injured populations are increasingly popular, and have the potential to leverage image analysis methods drawn from functional magnetic resonance imaging. However, power is a major concern for these studies, and is likely to vary regionally due to the distribution of lesion locations. Here, we outline general considerations for voxel-based methods, characterize the use of a nonparametric permutation test adapted from functional neuroimaging, and present methods for regional power analysis in lesion studies.
Kimberg, D. Y., Coslett, H. B., & Schwartz, M. F. (2007). Power in Voxel-based Lesion–Symptom Mapping. Retrieved from http://repository.upenn.edu/cog_neuro_pubs/5
Date Posted: 15 June 2011
This document has been peer reviewed.