Departmental Papers (CBE)

Document Type

Journal Article

Date of this Version

November 2003

Comments

Copyright American Physical Society. Reprinted from Physical Review Letters, Volume 91, Issue 19, Article 198101, November 2003, 4 pages.
Publisher URL: http://dx.doi.org/10.1103/PhysRevLett.91.198101

Abstract

We report the first measurements of the intrinsic strain fluctuations of living cells using a recently developed tracer correlation technique along with a theoretical framework for interpreting such data in heterogeneous media with nonthermal driving. The fluctuations’ spatial and temporal correlations indicate that the cytoskeleton can be treated as a course-grained continuum with power-law rheology, driven by a spatially random stress tensor field. Combined with recent cell rheology results, our data imply that intracellular stress fluctuations have a nearly 1/ω2 power spectrum, as expected for a continuum with a slowly evolving internal prestress.

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Date Posted: 20 December 2005

This document has been peer reviewed.